Knowledge engineering for health: A new discipline required to bridge the “ICT gap” between research and healthcare
Identifieur interne : 000253 ( Main/Exploration ); précédent : 000252; suivant : 000254Knowledge engineering for health: A new discipline required to bridge the “ICT gap” between research and healthcare
Auteurs : Tim Beck [Royaume-Uni] ; Sirisha Gollapudi [Royaume-Uni] ; S Ren Brunak [Danemark] ; Norbert Graf [Allemagne] ; Heinz U. Lemke [Allemagne] ; Debasis Dash [Inde] ; Iain Buchan [Royaume-Uni] ; Carlos Díaz [Espagne] ; Ferran Sanz [Espagne] ; Anthony J. Brookes [Royaume-Uni]Source :
- Human Mutation [ 1059-7794 ] ; 2012-05.
English descriptors
- KwdEn :
- Teeft :
- Biomedical informatics, Biomedical research, Clinical medicine, Computer modeling, Decision support, Ehrs, Free text, Future healthcare, Gen2phen project, Healthcare, Healthcare informatics, Healthcare providers, Human mutation, I4health, I4health concept, Informatics, Interdisciplinary experts, Knowledge engineering, Knowledge transmission, Latest research knowledge, Modeling, More facts, Patient data, Population level, Relevant advances, Research community, Research data, Research world, Treatment response, Wiley periodicals, Workshop delegates.
Abstract
Despite vast amount of money and research being channeled toward biomedical research, relatively little impact has been made on routine clinical practice. At the heart of this failure is the information and communication technology “chasm” that exists between research and healthcare. A new focus on “knowledge engineering for health” is needed to facilitate knowledge transmission across the research–healthcare gap. This discipline is required to engineer the bidirectional flow of data: processing research data and knowledge to identify clinically relevant advances and delivering these into healthcare use; conversely, making outcomes from the practice of medicine suitably available for use by the research community. This system will be able to self‐optimize in that outcomes for patients treated by decisions that were based on the latest research knowledge will be fed back to the research world. A series of meetings, culminating in the “I‐Health 2011” workshop, have brought together interdisciplinary experts to map the challenges and requirements for such a system. Here, we describe the main conclusions from these meetings. An “I4Health” interdisciplinary network of experts now exists to promote the key aims and objectives, namely “integrating and interpreting information for individualized healthcare,” by developing the “knowledge engineering for health” domain. Hum Mutat 33:797–802, 2012. © 2012 Wiley Periodicals, Inc.
Url:
DOI: 10.1002/humu.22066
Affiliations:
- Allemagne, Danemark, Espagne, Inde, Royaume-Uni
- Angleterre, Catalogne, Grand Manchester, Hovedstaden
- Barcelone, Copenhague, Manchester
- Université de Manchester
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Brookes</name><affiliation wicri:level="1"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Genetics, University of Leicester, Leicester</wicri:regionArea><wicri:noRegion>Leicester</wicri:noRegion></affiliation><affiliation wicri:level="1"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Genetics, University of Leicester, University Road, Leicester LE1 7RH</wicri:regionArea><wicri:noRegion>Leicester LE1 7RH</wicri:noRegion></affiliation></author></analytic><monogr></monogr><series><title level="j">Human Mutation</title><title level="j" type="abbrev">Hum. Mutat.</title><idno type="ISSN">1059-7794</idno><idno type="eISSN">1098-1004</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2012-05">2012-05</date><biblScope unit="volume">33</biblScope><biblScope unit="issue">5</biblScope><biblScope unit="page" from="797">797</biblScope><biblScope unit="page" to="802">802</biblScope></imprint><idno type="ISSN">1059-7794</idno></series><idno type="istex">3FD2846672BF3417AFDCE85F1A73A33521BFE299</idno><idno type="DOI">10.1002/humu.22066</idno><idno type="ArticleID">HUMU22066</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">1059-7794</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>ICT</term><term>I‐Health 2011</term><term>biomedical research</term><term>healthcare</term><term>personalized medicine</term></keywords><keywords scheme="Teeft" xml:lang="en"><term>Biomedical informatics</term><term>Biomedical research</term><term>Clinical medicine</term><term>Computer modeling</term><term>Decision support</term><term>Ehrs</term><term>Free text</term><term>Future healthcare</term><term>Gen2phen project</term><term>Healthcare</term><term>Healthcare informatics</term><term>Healthcare providers</term><term>Human mutation</term><term>I4health</term><term>I4health concept</term><term>Informatics</term><term>Interdisciplinary experts</term><term>Knowledge engineering</term><term>Knowledge transmission</term><term>Latest research knowledge</term><term>Modeling</term><term>More facts</term><term>Patient data</term><term>Population level</term><term>Relevant advances</term><term>Research community</term><term>Research data</term><term>Research world</term><term>Treatment response</term><term>Wiley periodicals</term><term>Workshop delegates</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Despite vast amount of money and research being channeled toward biomedical research, relatively little impact has been made on routine clinical practice. At the heart of this failure is the information and communication technology “chasm” that exists between research and healthcare. A new focus on “knowledge engineering for health” is needed to facilitate knowledge transmission across the research–healthcare gap. This discipline is required to engineer the bidirectional flow of data: processing research data and knowledge to identify clinically relevant advances and delivering these into healthcare use; conversely, making outcomes from the practice of medicine suitably available for use by the research community. This system will be able to self‐optimize in that outcomes for patients treated by decisions that were based on the latest research knowledge will be fed back to the research world. A series of meetings, culminating in the “I‐Health 2011” workshop, have brought together interdisciplinary experts to map the challenges and requirements for such a system. Here, we describe the main conclusions from these meetings. An “I4Health” interdisciplinary network of experts now exists to promote the key aims and objectives, namely “integrating and interpreting information for individualized healthcare,” by developing the “knowledge engineering for health” domain. Hum Mutat 33:797–802, 2012. © 2012 Wiley Periodicals, Inc.</div></front></TEI><affiliations><list><country><li>Allemagne</li><li>Danemark</li><li>Espagne</li><li>Inde</li><li>Royaume-Uni</li></country><region><li>Angleterre</li><li>Catalogne</li><li>Grand Manchester</li><li>Hovedstaden</li></region><settlement><li>Barcelone</li><li>Copenhague</li><li>Manchester</li></settlement><orgName><li>Université de Manchester</li></orgName></list><tree><country name="Royaume-Uni"><noRegion><name sortKey="Beck, Tim" sort="Beck, Tim" uniqKey="Beck T" first="Tim" last="Beck">Tim Beck</name></noRegion><name sortKey="Brookes, Anthony J" sort="Brookes, Anthony J" uniqKey="Brookes A" first="Anthony J." last="Brookes">Anthony J. Brookes</name><name sortKey="Brookes, Anthony J" sort="Brookes, Anthony J" uniqKey="Brookes A" first="Anthony J." last="Brookes">Anthony J. Brookes</name><name sortKey="Buchan, Iain" sort="Buchan, Iain" uniqKey="Buchan I" first="Iain" last="Buchan">Iain Buchan</name><name sortKey="Gollapudi, Sirisha" sort="Gollapudi, Sirisha" uniqKey="Gollapudi S" first="Sirisha" last="Gollapudi">Sirisha Gollapudi</name></country><country name="Danemark"><noRegion><name sortKey="Brunak, S Ren" sort="Brunak, S Ren" uniqKey="Brunak S" first="S Ren" last="Brunak">S Ren Brunak</name></noRegion><name sortKey="Brunak, S Ren" sort="Brunak, S Ren" uniqKey="Brunak S" first="S Ren" last="Brunak">S Ren Brunak</name></country><country name="Allemagne"><noRegion><name sortKey="Graf, Norbert" sort="Graf, Norbert" uniqKey="Graf N" first="Norbert" last="Graf">Norbert Graf</name></noRegion><name sortKey="Lemke, Heinz U" sort="Lemke, Heinz U" uniqKey="Lemke H" first="Heinz U." last="Lemke">Heinz U. 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